Discovery of a multi-bond forming, four-step tandem process: construction of drug-like polycyclic scaffolds.
نویسندگان
چکیده
A one-pot tandem process involving an Overman rearrangement, ring closing enyne metathesis and a hydrogen bonding directed Diels-Alder reaction has been developed for the efficient diastereoselective synthesis of functionalised amino substituted tetralin and indene ring systems.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 64 شماره
صفحات -
تاریخ انتشار 2012